Dr Pedro Estrela, Associate Professor and Director at the Department of Electronic & Electrical Engineering at the University of Bath, presents 'Electrochemical Biosensors for Medical and Environmental Applications.
Abstract
There is a great need for low-cost intelligent biochips capable of massive parallel detection to be used in portable instrumentation. Electrochemical methods are inherently low-cost, miniaturisable and easily integrated into multiplexed systems for the parallel screening of panels of biomarkers.
Of particular interest are biologically sensitive field-effect transistors (BioFETs) and impedance-based sensors. We will exemplify the use of synthetic molecules such as DNA aptamers and peptide aptamers (Affimers), as alternatives to antibodies, as well as oligonucleotide-based approaches in impedance and BioFET sensors for the detection of a range of biomarkers in medical diagnosis and for water/wastewater monitoring.
Biography
Dr Pedro Estrela has a background in Physics (degree and Masters from the University of Lisbon, PhD from the University of Amsterdam) and started working in the field of biosensors in 2000 (University of Cambridge until 2008 and University of Bath since 2008).
Dr Estrela’s research focuses on the development of label-free electrical, electrochemical and plasmonic biosensors for a wide range of applications such as medical diagnostics and environmental monitoring. He is the Director of the recently
established Centre for Biosensors, Bioelectronics and Biodevices (C3Bio),Theme Leader (Healthcare Technologies) at the Centre
for Sustainable Chemical Technologies, Theme Leader (Sensors & Data) at the Water Innovation and Research Centre, member of the Leadership Team of the Centre for Therapeutic Innovation.